Cellular and gene therapy for major histocompatibility complex class II deficiency.
نویسندگان
چکیده
Major histocompatibility complex (MHC) class II deficiency is a primary immunodeficiency. Lentiviral vectors are used for gene therapy in a mouse model of this disease. In addition, by a direct genetic correction approach, a diagnostic test to determine which of the four MHC II genes is defective in new MHC II-deficiency patients has been optimized.
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ورودعنوان ژورنال:
- News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society
دوره 19 شماره
صفحات -
تاریخ انتشار 2004